Walking a short distance down Via Ghislieri, on the right, one reaches the crypt of the cathedral with the Tomb of the Bishops, built starting in 1597 where, around 1557, the Confraternity of Mercy and Death had built the Oratory; on the stone lintel of the portal, later adapted to the crypt, one can still read: TEMPLUM SOCIETATIS MISERICORDIAE. The small bell gable, designed by Lucidio Benvignati, was built in the years 1847-50. In the years 1972-74, with the casting of architect Remo Radicioni, substantial changes were made in the interior to create the tomb of four bishops of Ripatransone (Recco, Alessandrini, Nicolai, Boschi), on whose stele stands a polychrome Crucifixion by Ascoli ceramist Giuseppe Marinucci; behind the new high altar in polished and hammered travertine, a wooden Crucifix (17th-18th centuries), already in the seminary's inner chapel, was placed. The most beautiful altar is the one on the left, dedicated to Our Lady of Sorrows, installed in the early 19th century, probably the work of Giovanni Moschetti of Montegiorgio, who had moved to Ripatransone; it was refurbished in the early 20th century; under the altar mensa is an image of the Dead Christ by Giuseppe Manzo of Lecce (early 20th century).

The Liturgical organ was built in 1909 by Verati of Bologna and was restored in 2003. On the walls (repainted in 1999): at the back, the 14 stations of the "Way of the Cross" (1974); eight artistic gilded wooden appliches (sec. XIX); small framed canvas depicting the procession of the Dead Christ, work (2000) by Mario Vespasiani, In the sacristy are kept the seven stations of the "Via Matris," engravings by Giuseppe Capparoni; in the vestments of the Confratelli: "The Virgin of the Seven Sorrows," small canvas by Luigi Corsi from Ripano (second half of the 1700s); a carpet for the Dead Christ, supported by three Angels, painted on the back wall by Pietro Capocasa from Ripano (18th cent.).